5 Spinocerebellar Ataxia Type 2

نویسندگان

  • Luis Velázquez-Pérez
  • Roberto Rodríguez-Labrada
  • Hans-Joachim Freund
  • Georg Auburger
چکیده

The autosomal dominant cerebellar ataxias (ADCA) are a clinically, pathologically and genetically heterogeneous group of neurodegenerative disorders caused by degeneration of cerebellum and its afferent and efferent connections. The degenerative process may additionally involves the pontomedullar systems, pyramidal tracts, basal ganglia, cerebral cortex, peripheral nerves (ADCA I) and the retina (ADCA II), or can be limited to the cerebellum (ADCA III) (Harding et al., 1993).

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تاریخ انتشار 2012